The number one cause of this issue is incorrectly loaded label stock. See this article for label stock loading tips.
There are also adjustments that can be made to fix this issue. However, before making any adjustments please keep in mind that all adjustments are made from the printer's perspective. Left Margin offset is the printer's left (your right). The image is printed up-side-down if you are looking at it as it prints, but from the printer's perspective, it is printing right-side-up, etc.
Left Margin Offset. This adjustment is found in the printer preferences area of the printer driver. If you see white space on the right (printer's left) side of the label and overlap on the opposite side, decrease the Left Margin Offset value (negative numbers are allowed). If you see white space on the left (printer's right) side of the label and overlap on the opposite side increase the value. See the example below:
Note: Oftentimes a space on the right (printer's left) side indicates a liner margin around the label that is not being accounted for. The printer is factory calibrated for a 1/16" (2mm) liner margin between the edge of the label and the edge of the roll. A larger margin around the label will cause a space on the right (printer's left).
Page Size does not match Label Size. If you are using BarTender follow this label setup guide. Often, the page size is not large enough for the label. If this is the case you may see white space on the right (printer's left) side of the label and no image overlap on the opposite side. This indicates that the page size needs to be increased. Increase the page size through the printer preferences enough to cover the label.
Edge Scan. Every few labels, the printer will scan your media's edge to find the correct left margin starting position. You can increase this scan frequency or turn it off completely if it is not detecting the edge accurately. This can happen on circular labels more easily. Go to Print Hub on PC only to adjust this setting. Find the Print Alignment Tab. Click More Settings.